Windows
Windows 10/11 · 64-bit · installer with automatic updates
Download for WindowsLibrary Aligner
MGI WashU · Sequencing Suite
Cross-platform library analysis for FASTQ acquisition and preparation, guide-sequence counting, representation and contamination QC, cutting analysis, and retained advanced workflows.
macOS
macOS 14 or later · Apple Silicon · installer package
Download for macOS Portable Apple Silicon app ZIPThe macOS build may trail the current Windows release. After installation, Library Aligner checks its platform release feed on launch and prompts before restarting into an available update.
Run the core alignment workflow
- Install Library Aligner from the button for your platform above.
- Load a reference library and select the folder containing the FASTQ files.
- Run Counts to create a count table, or run Cutting with the loaded reference library and FASTQ folder.
- Load a count table to create the Check Rep contamination and representation graphs.
Command-line and advanced use
- The desktop application includes an Advanced workspace for STARS, protein alignment, demultiplexing, off-target analysis, distance clustering, UMI counting, and result utilities.
- The packaged
library-alignercommand supports one-shot workflows for scripts and agents; runlibrary-aligner --helpto list commands. - Advanced users can download the portable Windows ZIP or portable Apple Silicon app ZIP.